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Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod

Multiple sclerosis (MS) is an immune-mediated demyelinating disease that alters central nervous system (CNS) functions. Relapsing-remitting MS (RRMS) is the most common form, which can transform into secondary-progressive MS (SPMS) that is associated with progressive neurodegeneration. Single-nucleu...

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Detalles Bibliográficos
Autores principales: Kihara, Yasuyuki, Zhu, Yunjiao, Jonnalagadda, Deepa, Romanow, William, Palmer, Carter, Siddoway, Benjamin, Rivera, Richard, Dutta, Ranjan, Trapp, Bruce D., Chun, Jerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247150/
https://www.ncbi.nlm.nih.gov/pubmed/35783097
http://dx.doi.org/10.3389/fncel.2022.918041