MIR205HG/LEADR Long Noncoding RNA Binds to Primed Proximal Regulatory Regions in Prostate Basal Cells Through a Triplex- and Alu-Mediated Mechanism

Aside serving as host gene for miR-205, MIR205HG transcribes for a chromatin-associated long noncoding RNA (lncRNA) able to restrain the differentiation of prostate basal cells, thus being reannotated as LEADR (Long Epithelial Alu-interacting Differentiation-related RNA). We previously showed the pr...

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Detalles Bibliográficos
Autores principales: Bezzecchi, Eugenia, Pagani, Giulia, Forte, Barbara, Percio, Stefano, Zaffaroni, Nadia, Dolfini, Diletta, Gandellini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247157/
https://www.ncbi.nlm.nih.gov/pubmed/35784469
http://dx.doi.org/10.3389/fcell.2022.909097

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