Cargando…

An Unusual U2AF2 Inhibits Splicing and Attenuates the Virulence of the Human Protozoan Parasite Entamoeba histolytica

E. histolytica is the etiological agent of intestinal amebiasis and liver abscesses, which still poses public health threat globally. Metronidazole is the drug of choice against amebiasis. However, metronidazole-resistant amoebic clinical isolates and strains have been reported recently, challenging...

Descripción completa

Detalles Bibliográficos
Autores principales:	González-Blanco, Gretter, García-Rivera, Guillermina, Talmás-Rohana, Patricia, Orozco, Ester, Galindo-Rosales, José Manuel, Vélez, Cristina, Salucedo-Cárdenas, Odila, Azuara-Liceaga, Elisa, Rodríguez-Rodríguez, Mario Alberto, Nozaki, Tomoyoshi, Valdés, Jesús
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247205/ https://www.ncbi.nlm.nih.gov/pubmed/35782149 http://dx.doi.org/10.3389/fcimb.2022.888428

Ejemplares similares

Postsplicing-Derived Full-Length Intron Circles in the Protozoan Parasite Entamoeba histolytica
por: Mendoza-Figueroa, María S., et al.
Publicado: (2018)

Lysine Methyltransferase EhPKMT2 Is Involved in the In Vitro Virulence of Entamoeba histolytica
por: Munguía-Robledo, Susana, et al.
Publicado: (2023)

The Entamoeba histolytica Syf1 Homolog Is Involved in the Splicing of AG-Dependent and AG-Independent Transcripts
por: Torres-Cifuentes, Diana M., et al.
Publicado: (2018)

Promoter-Bound Full-Length Intronic Circular RNAs-RNA Polymerase II Complexes Regulate Gene Expression in the Human Parasite Entamoeba histolytica
por: García-Lerena, Jesús Alberto, et al.
Publicado: (2022)

Dramatic Increase in Glycerol Biosynthesis upon Oxidative Stress in the Anaerobic Protozoan Parasite Entamoeba histolytica
por: Husain, Afzal, et al.
Publicado: (2012)

PTEN differentially regulates endocytosis, migration, and proliferation in the enteric protozoan parasite Entamoeba histolytica
por: Kadri, Samia, et al.
Publicado: (2022)

Novel Transmembrane Receptor Involved in Phagosome Transport of Lysozymes and β-Hexosaminidase in the Enteric Protozoan Entamoeba histolytica
por: Furukawa, Atsushi, et al.
Publicado: (2012)

Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica
por: Husain, Afzal, et al.
Publicado: (2011)

Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica
por: Jeelani, Ghulam, et al.
Publicado: (2017)

Endoplasmic reticulum‐resident Rab8A GTPase is involved in phagocytosis in the protozoan parasite Entamoeba histolytica
por: Hanadate, Yuki, et al.
Publicado: (2016)

Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica
por: Nakada-Tsukui, Kumiko, et al.
Publicado: (2022)

Mass Spectrometric Analysis of l-Cysteine Metabolism: Physiological Role and Fate of l-Cysteine in the Enteric Protozoan Parasite Entamoeba histolytica
por: Jeelani, Ghulam, et al.
Publicado: (2014)

Rab7D small GTPase is involved in phago‐, trogocytosis and cytoskeletal reorganization in the enteric protozoan Entamoeba histolytica
por: Saito‐Nakano, Yumiko, et al.
Publicado: (2020)

Glycerol biosynthetic pathway plays an essential role in proliferation and antioxidative defense in the human enteric protozoan parasite Entamoeba histolytica
por: Jeelani, Ghulam, et al.
Publicado: (2023)

Telomeric Repeat-Binding Factor Homologs in Entamoeba histolytica: New Clues for Telomeric Research
por: Rendón-Gandarilla, Francisco Javier, et al.
Publicado: (2018)

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica
por: Nakada-Tsukui, Kumiko, et al.
Publicado: (2019)

Identification of the phospholipid lysobisphosphatidic acid in the protozoan Entamoeba histolytica: An active molecule in endocytosis
por: Castellanos-Castro, Silvia, et al.
Publicado: (2015)

Near-chromosome level genome assembly reveals ploidy diversity and plasticity in the intestinal protozoan parasite Entamoeba histolytica
por: Kawano-Sugaya, Tetsuro, et al.
Publicado: (2020)

Non-vesicular Lipid Transport Machinery in Entamoeba histolytica
por: Das, Koushik, et al.
Publicado: (2018)

Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2
por: Watanabe, Natsuki, et al.
Publicado: (2023)

Trend of Entamoeba histolytica infestation in Kolkata
por: Mukherjee, Avik K, et al.
Publicado: (2010)

A Nuclear Family A DNA Polymerase from Entamoeba histolytica Bypasses Thymine Glycol
por: Pastor-Palacios, Guillermo, et al.
Publicado: (2010)

Immune Response of Amebiasis and Immune Evasion by Entamoeba histolytica
por: Nakada-Tsukui, Kumiko, et al.
Publicado: (2016)

The Sole DNA Ligase in Entamoeba histolytica Is a High-Fidelity DNA Ligase Involved in DNA Damage Repair
por: Azuara-Liceaga, Elisa, et al.
Publicado: (2018)

Unexplored Molecular Features of the Entamoeba histolytica RNA Lariat Debranching Enzyme Dbr(1) Expression Profile
por: Valdés, Jesús, et al.
Publicado: (2018)

Molecular Dissection of Phagocytosis by Proteomic Analysis in Entamoeba histolytica
por: Watanabe, Natsuki, et al.
Publicado: (2023)

Corrigendum: The sole DNA ligase in Entamoeba histolytica is a high-fidelity DNA ligase involved in DNA damage repair
por: Azuara-Liceaga, Elisa, et al.
Publicado: (2022)

Eukaryotic translation initiation factor 5A and its posttranslational modifications play an important role in proliferation and potentially in differentiation of the human enteric protozoan parasite Entamoeba histolytica
por: Jeelani, Ghulam, et al.
Publicado: (2021)

Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica
por: Ehrenkaufer, Gretchen M, et al.
Publicado: (2007)

Genome-Wide Analysis of Known and Potential Tetraspanins in Entamoeba histolytica
por: Tomii, Kentaro, et al.
Publicado: (2019)

The Cell Surface Proteome of Entamoeba histolytica
por: Biller, Laura, et al.
Publicado: (2014)

ArfX2 GTPase Regulates Trafficking From the Trans-Golgi to Lysosomes and Is Necessary for Liver Abscess Formation in the Protozoan Parasite Entamoeba histolytica
por: Saito-Nakano, Yumiko, et al.
Publicado: (2021)

AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolytica
por: Somlata, et al.
Publicado: (2017)

Role of the Gut Microbiota of Children in Diarrhea Due to the Protozoan Parasite Entamoeba histolytica
por: Gilchrist, Carol A., et al.
Publicado: (2016)

The NF-κB Pathway: Modulation by Entamoeba histolytica and Other Protozoan Parasites
por: Chadha, Attinder, et al.
Publicado: (2021)

Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites
por: Wang, Shanshan, et al.
Publicado: (2022)

Corrigendum: ArfX2 GTPase Regulates Trafficking From the Trans-Golgi to Lysosomes and Is Necessary for Liver Abscess Formation in the Protozoan Parasite Entamoeba histolytica
por: Saito-Nakano, Yumiko, et al.
Publicado: (2022)

Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact
por: Santos, Herbert J., et al.
Publicado: (2022)

Erythrophagocytosis in Entamoeba histolytica and Entamoeba dispar: A Comparative Study
por: Talamás-Lara, Daniel, et al.
Publicado: (2014)

Protein Sumoylation Is Crucial for Phagocytosis in Entamoeba histolytica Trophozoites
por: Díaz-Hernández, Mitzi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_eq6hrghigg26dr3jgbr2lsem9d