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Resolving SARS-CoV-2 CD4(+) T cell specificity via reverse epitope discovery

The current strategy to detect immunodominant T cell responses focuses on the antigen, employing large peptide pools to screen for functional cell activation. However, these approaches are labor and sample intensive and scale poorly with increasing size of the pathogen peptidome. T cell receptors (T...

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Detalles Bibliográficos
Autores principales:	Pogorelyy, Mikhail V., Rosati, Elisa, Minervina, Anastasia A., Mettelman, Robert C., Scheffold, Alexander, Franke, Andre, Bacher, Petra, Thomas, Paul G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247234/ https://www.ncbi.nlm.nih.gov/pubmed/35841887 http://dx.doi.org/10.1016/j.xcrm.2022.100697

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