Vγ2 x PD-L1, a Bispecific Antibody Targeting Both the Vγ2 TCR and PD-L1, Improves the Anti-Tumor Response of Vγ2Vδ2 T Cell

The potent cytotoxic property of Vγ2Vδ2 T cells makes them attractive for adoptive T cell transfer therapy. The transfusing of the expanded Vγ2Vδ2 T cells into cancer patients shows well-tolerated, but the clinical response rates are required to be improved, implying that there is still an unmet eff...

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Detalles Bibliográficos
Autores principales: Yang, Rui, He, Qing, Zhou, Hui, Gong, Cheng, Wang, Xing, Song, Xingpan, Luo, Fang, Lei, Yang, Ni, Qian, Wang, Zili, Xu, Shasha, Xue, Yan, Zhang, Man, Wen, Haimei, Fang, Lijuan, Zeng, Liang, Yan, Yongxiang, Shi, Jian, Zhang, Jing, Yi, Jizu, Zhou, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247338/
https://www.ncbi.nlm.nih.gov/pubmed/35784353
http://dx.doi.org/10.3389/fimmu.2022.923969

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