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Reforming the Chimeric Antigen Receptor by Peptide Towards Optimized CAR T Cells With Enhanced Anti-Cancer Potency and Safety

The emerging chimeric antigen receptor (CAR) T cell revolutionized the clinic treatment of hematological cancers, but meet its Waterloo in solid tumor therapy. Although there exist many reasons for this limitation, one of the largest challenges is the scarcity of recognition for tumor cells, resulti...

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Detalles Bibliográficos
Autores principales:	Liu, Cuijuan, Li, Lin, Gao, Fan, Zhou, Jundong, Qin, Yingzhou, Yuan, Xin, Yang, Guang, Zhu, Yimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247402/ https://www.ncbi.nlm.nih.gov/pubmed/35782491 http://dx.doi.org/10.3389/fbioe.2022.928169

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