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Impact of Neoadjuvant Bevacizumab on Neuroradiographic Response and Histological Findings Related to Tumor Stemness and the Hypoxic Tumor Microenvironment in Glioblastoma: Paired Comparison Between Newly Diagnosed and Recurrent Glioblastomas
BACKGROUND: Previously, we reported that bevacizumab (Bev) produces histological and neuroradiographic alterations including changes in tumor oxygenation, induction of an immunosupportive tumor microenvironment, and inhibition of stemness. To confirm how those effects vary during Bev therapy, paired...
Autores principales: | Takei, Jun, Fukasawa, Nei, Tanaka, Toshihide, Yamamoto, Yohei, Tamura, Ryota, Sasaki, Hikaru, Akasaki, Yasuharu, Kamata, Yuko, Murahashi, Mutsunori, Shimoda, Masayuki, Murayama, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247463/ https://www.ncbi.nlm.nih.gov/pubmed/35785200 http://dx.doi.org/10.3389/fonc.2022.898614 |
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