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Oligomerization and Spatial Distribution of Kvβ1.1 and Kvβ2.1 Regulatory Subunits

Members of the regulatory Kvβ family modulate the kinetics and traffic of voltage-dependent K(+) (Kv) channels. The crystal structure of Kv channels associated with Kvβ peptides suggests a α4/β4 composition. Although Kvβ2 and Kvβ1 form heteromers, evidence supports that only Kvβ2.1 forms tetramers i...

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Detalles Bibliográficos
Autores principales: Roig, Sara R., Cassinelli, Silvia, Zeug, Andre, Ponimaskin, Evgeni, Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247503/
https://www.ncbi.nlm.nih.gov/pubmed/35784882
http://dx.doi.org/10.3389/fphys.2022.930769