MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling

Epithelial-mesenchymal transition (EMT) is known to be involved in airway remodeling and fibrosis of bronchial asthma. However, the molecular mechanisms leading to EMT have yet to be fully clarified. The current study was designed to reveal the potential mechanism of microRNA-21 (miR-21) and poly (A...

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Detalles Bibliográficos
Autores principales: Zhang, Shiqing, Sun, Peng, Xiao, Xinru, Hu, Yujie, Qian, Yan, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247709/
https://www.ncbi.nlm.nih.gov/pubmed/35766002
http://dx.doi.org/10.4196/kjpp.2022.26.4.239

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