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Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq

There is an increased awareness that the use of animals for compound-induced developmental neurotoxicity (DNT) testing has limitations. Animal-free innovations, especially the ones based on human stem cell-based models are pivotal in studying DNT since they can mimic processes relevant to human brai...

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Detalles Bibliográficos
Autores principales:	de Leeuw, Victoria C., van Oostrom, Conny T.M., Wackers, Paul F.K., Pennings, Jeroen L.A., Hodemaekers, Hennie M., Piersma, Aldert H., Hessel, Ellen V.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247748/ https://www.ncbi.nlm.nih.gov/pubmed/35700809 http://dx.doi.org/10.1016/j.chemosphere.2022.135298

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