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Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center

OBJECTIVES: To identify the etiology and outcomes of new onset seizure in adult patients presenting to the Emergency Department (ED), to improve knowledge among healthcare providers regarding diagnosis and hence improve the outcomes. METHODS: This was a descriptive retrospective study conducted at t...

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Autores principales: Ali, Noman, Dharamshi, Hasnain Abbas, Mustahsan, Syed, Noorani, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247801/
https://www.ncbi.nlm.nih.gov/pubmed/35799711
http://dx.doi.org/10.12669/pjms.38.5.4411
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author Ali, Noman
Dharamshi, Hasnain Abbas
Mustahsan, Syed
Noorani, Suman
author_facet Ali, Noman
Dharamshi, Hasnain Abbas
Mustahsan, Syed
Noorani, Suman
author_sort Ali, Noman
collection PubMed
description OBJECTIVES: To identify the etiology and outcomes of new onset seizure in adult patients presenting to the Emergency Department (ED), to improve knowledge among healthcare providers regarding diagnosis and hence improve the outcomes. METHODS: This was a descriptive retrospective study conducted at the Emergency Department of Aga Khan University Hospital, Karachi, Pakistan. Adult patients (18 years and above), presented to the ED from January 01, 2019 to June 30, 2020, with new onset seizure were included consecutively. Descriptive data on patient demographics, seizure types, investigations performed, final diagnosis and disposition were collected retrospectively from patient’s file and electronic record. Etiologies of seizure were classified as structural (metabolic, trauma, infection), genetic or idiopathic. The immediate outcomes were reported as hospitalization or discharge from the ED. RESULTS: In total 198 patients with new onset seizure were included. Majority of the patients were found in middle age group i.e., 35 to 65 years (44.4%). Gender distribution showed slightly higher percentage of females (55.1%). Generalized tonic clonic seizures were found to be the most common type of seizures (74.2%), followed by generalized tonic (12.1%) and focal onset aware seizures (7.5%). Out of total patients no cause was identified in eight patients (4%), whereas in total confirmed causes of new onset seizures, structural lesions of brain were found to be the most common cause (89.6%%), including neurological (23.6%), infectious (4.2%), systemic (13%), metabolic (7%) and toxicological (4%) causes respectively. CONCLUSION: This study explores the various etiologies of new onset seizures in adult patients presenting to the ED. The study emphasizes the need for a local guideline for the investigation of new onset seizures in adult patients that would direct emergency physicians in respect of appropriate management, thus to ensure better quality of patient care and outcomes.
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spelling pubmed-92478012022-07-06 Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center Ali, Noman Dharamshi, Hasnain Abbas Mustahsan, Syed Noorani, Suman Pak J Med Sci Original Article OBJECTIVES: To identify the etiology and outcomes of new onset seizure in adult patients presenting to the Emergency Department (ED), to improve knowledge among healthcare providers regarding diagnosis and hence improve the outcomes. METHODS: This was a descriptive retrospective study conducted at the Emergency Department of Aga Khan University Hospital, Karachi, Pakistan. Adult patients (18 years and above), presented to the ED from January 01, 2019 to June 30, 2020, with new onset seizure were included consecutively. Descriptive data on patient demographics, seizure types, investigations performed, final diagnosis and disposition were collected retrospectively from patient’s file and electronic record. Etiologies of seizure were classified as structural (metabolic, trauma, infection), genetic or idiopathic. The immediate outcomes were reported as hospitalization or discharge from the ED. RESULTS: In total 198 patients with new onset seizure were included. Majority of the patients were found in middle age group i.e., 35 to 65 years (44.4%). Gender distribution showed slightly higher percentage of females (55.1%). Generalized tonic clonic seizures were found to be the most common type of seizures (74.2%), followed by generalized tonic (12.1%) and focal onset aware seizures (7.5%). Out of total patients no cause was identified in eight patients (4%), whereas in total confirmed causes of new onset seizures, structural lesions of brain were found to be the most common cause (89.6%%), including neurological (23.6%), infectious (4.2%), systemic (13%), metabolic (7%) and toxicological (4%) causes respectively. CONCLUSION: This study explores the various etiologies of new onset seizures in adult patients presenting to the ED. The study emphasizes the need for a local guideline for the investigation of new onset seizures in adult patients that would direct emergency physicians in respect of appropriate management, thus to ensure better quality of patient care and outcomes. Professional Medical Publications 2022 /pmc/articles/PMC9247801/ /pubmed/35799711 http://dx.doi.org/10.12669/pjms.38.5.4411 Text en Copyright: © Pakistan Journal of Medical Sciences https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ali, Noman
Dharamshi, Hasnain Abbas
Mustahsan, Syed
Noorani, Suman
Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title_full Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title_fullStr Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title_full_unstemmed Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title_short Etiology and outcomes of new onset seizure in adult patients: A clinical experience from emergency department of a tertiary care center
title_sort etiology and outcomes of new onset seizure in adult patients: a clinical experience from emergency department of a tertiary care center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247801/
https://www.ncbi.nlm.nih.gov/pubmed/35799711
http://dx.doi.org/10.12669/pjms.38.5.4411
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