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Engineered Nanoscale Lipid-Based Formulation as Potential Enhancer of Gefitinib Lymphatic Delivery: Cytotoxicity and Apoptotic Studies Against the A549 Cell Line

The present study aimed to engineer a nanoscale lipid-based lymphatic drug delivery system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic metastasis of lung cancer. The nanoscale lipid-based systems including GEF-SLN, GEF-NLC, and GEF-LE were prepared and pharmaceutic...

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Detalles Bibliográficos
Autores principales: Sherif, Abdelrahman Y., Harisa, Gamaleldin I., Alanazi, Fars K., Nasr, Fahd A., Alqahtani, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247939/
https://www.ncbi.nlm.nih.gov/pubmed/35773422
http://dx.doi.org/10.1208/s12249-022-02332-7