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Engineered Nanoscale Lipid-Based Formulation as Potential Enhancer of Gefitinib Lymphatic Delivery: Cytotoxicity and Apoptotic Studies Against the A549 Cell Line
The present study aimed to engineer a nanoscale lipid-based lymphatic drug delivery system with D-α-Tocopherol polyethylene glycol 1000 succinate to combat the lymphatic metastasis of lung cancer. The nanoscale lipid-based systems including GEF-SLN, GEF-NLC, and GEF-LE were prepared and pharmaceutic...
Autores principales: | Sherif, Abdelrahman Y., Harisa, Gamaleldin I., Alanazi, Fars K., Nasr, Fahd A., Alqahtani, Ali S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247939/ https://www.ncbi.nlm.nih.gov/pubmed/35773422 http://dx.doi.org/10.1208/s12249-022-02332-7 |
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