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(19)F Electron-Nuclear Double Resonance Reveals Interaction between Redox-Active Tyrosines across the α/β Interface of E. coli Ribonucleotide Reductase
[Image: see text] Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, thereby playing a key role in DNA replication and repair. Escherichia coli class Ia RNR is an α(2)β(2) enzyme complex that uses a reversible multistep radical transfer (RT) over 32 Å...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248007/ https://www.ncbi.nlm.nih.gov/pubmed/35652913 http://dx.doi.org/10.1021/jacs.2c02906 |