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(19)F Electron-Nuclear Double Resonance Reveals Interaction between Redox-Active Tyrosines across the α/β Interface of E. coli Ribonucleotide Reductase

[Image: see text] Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, thereby playing a key role in DNA replication and repair. Escherichia coli class Ia RNR is an α(2)β(2) enzyme complex that uses a reversible multistep radical transfer (RT) over 32 Å...

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Detalles Bibliográficos
Autores principales: Meyer, Andreas, Kehl, Annemarie, Cui, Chang, Reichardt, Fehmke A. K., Hecker, Fabian, Funk, Lisa-Marie, Ghosh, Manas K., Pan, Kuan-Ting, Urlaub, Henning, Tittmann, Kai, Stubbe, JoAnne, Bennati, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248007/
https://www.ncbi.nlm.nih.gov/pubmed/35652913
http://dx.doi.org/10.1021/jacs.2c02906