Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?

Corticosteroids were the first drugs proven to reduce mortality in Covid-19. In June 2020, the RECOVERY group announced the results of their seminal trial showing dexamethasone 6 mg per day was able to reduce 28-day mortality in hospitalized patients with Covid needing supplemental oxygen or mechani...

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Detalles Bibliográficos
Autores principales: Cordeiro Veiga, Viviane, Biasi Cavalcanti, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248174/
https://www.ncbi.nlm.nih.gov/pubmed/35777764
http://dx.doi.org/10.1183/13993003.01220-2022
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author Cordeiro Veiga, Viviane
Biasi Cavalcanti, Alexandre
author_facet Cordeiro Veiga, Viviane
Biasi Cavalcanti, Alexandre
author_sort Cordeiro Veiga, Viviane
collection PubMed
description Corticosteroids were the first drugs proven to reduce mortality in Covid-19. In June 2020, the RECOVERY group announced the results of their seminal trial showing dexamethasone 6 mg per day was able to reduce 28-day mortality in hospitalized patients with Covid needing supplemental oxygen or mechanical ventilation [1]. Meta-analysis from randomized controlled trials (RCT) in Covid-19 patients confirmed RECOVERY results [2]. In those RCTs, corticosteroid doses were low (dexamethasone 6 mg per day) or intermediate (dexamethasone up to 20mg per day).
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spelling pubmed-92481742022-07-05 Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19? Cordeiro Veiga, Viviane Biasi Cavalcanti, Alexandre Eur Respir J Editorial Corticosteroids were the first drugs proven to reduce mortality in Covid-19. In June 2020, the RECOVERY group announced the results of their seminal trial showing dexamethasone 6 mg per day was able to reduce 28-day mortality in hospitalized patients with Covid needing supplemental oxygen or mechanical ventilation [1]. Meta-analysis from randomized controlled trials (RCT) in Covid-19 patients confirmed RECOVERY results [2]. In those RCTs, corticosteroid doses were low (dexamethasone 6 mg per day) or intermediate (dexamethasone up to 20mg per day). European Respiratory Society 2022-07-01 /pmc/articles/PMC9248174/ /pubmed/35777764 http://dx.doi.org/10.1183/13993003.01220-2022 Text en Copyright ©The authors 2022 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Editorial
Cordeiro Veiga, Viviane
Biasi Cavalcanti, Alexandre
Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title_full Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title_fullStr Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title_full_unstemmed Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title_short Are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe Covid-19?
title_sort are intravenous corticosteroid pulses superior to low dose corticosteroids in patients with severe covid-19?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248174/
https://www.ncbi.nlm.nih.gov/pubmed/35777764
http://dx.doi.org/10.1183/13993003.01220-2022
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