SNTA1-deficient human cardiomyocytes demonstrate hypertrophic phenotype and calcium handling disorder

BACKGROUND: α-1-syntrophin (SNTA1), a protein encoded by SNTA1, is highly expressed in human cardiomyocytes. Mutations in SNTA1 are associated with arrhythmia and cardiomyopathy. Previous research on SNTA1 has been based on non-human cardiomyocytes. This study was designed to identify the phenotype...

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Detalles Bibliográficos
Autores principales: Dong, Tao, Zhao, Yan, Jin, Hai-Feng, Shen, Lei, Lin, Yan, Si, Long-Long, Chen, Li, Liu, Ji-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248201/
https://www.ncbi.nlm.nih.gov/pubmed/35773684
http://dx.doi.org/10.1186/s13287-022-02955-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248201/
https://www.ncbi.nlm.nih.gov/pubmed/35773684
http://dx.doi.org/10.1186/s13287-022-02955-4

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