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SNTA1-deficient human cardiomyocytes demonstrate hypertrophic phenotype and calcium handling disorder

BACKGROUND: α-1-syntrophin (SNTA1), a protein encoded by SNTA1, is highly expressed in human cardiomyocytes. Mutations in SNTA1 are associated with arrhythmia and cardiomyopathy. Previous research on SNTA1 has been based on non-human cardiomyocytes. This study was designed to identify the phenotype...

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Detalles Bibliográficos
Autores principales:	Dong, Tao, Zhao, Yan, Jin, Hai-Feng, Shen, Lei, Lin, Yan, Si, Long-Long, Chen, Li, Liu, Ji-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248201/ https://www.ncbi.nlm.nih.gov/pubmed/35773684 http://dx.doi.org/10.1186/s13287-022-02955-4

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