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Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells

The pathological consequences leading to primary storage, autophagy impairment, impaired mitochondrial dynamics, and endoplasmic reticulum (ER) stress on neural cell dysfunction and apoptosis in metachromatic leukodystrophy (MLD) have been poorly elucidated. In the present study, we generated 2 cell...

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Detalles Bibliográficos
Autores principales:	Hossain, Mohammad Arif, Hasegawa-Ogawa, Minami, Manome, Yoko, Igarashi, Miki, Wu, Chen, Suzuki, Ken, Igarashi, Junko, Iwamoto, Takeo, Okano, Hirotaka James, Eto, Yoshikatsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248224/ https://www.ncbi.nlm.nih.gov/pubmed/35782608 http://dx.doi.org/10.1016/j.ymgmr.2022.100852

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