Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)

Neoadjuvant therapy (NAT) in breast cancer is administered to downstage the tumor, de-escalate surgery, and provide prognostic information that can be used to tailor subsequent adjuvant therapy. In this respect, the pathological evaluation of both pre-NAT biopsies and post-NAT surgical specimens is...

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Autores principales: Fusco, Nicola, Rizzo, Antonio, Costarelli, Leopoldo, Santinelli, Alfredo, Cerbelli, Bruna, Scatena, Cristian, Macrì, Ettore, Pietribiasi, Francesca, d’Amati, Giulia, Sapino, Anna, Castellano, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2022
Materias:
Guidelines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248246/
https://www.ncbi.nlm.nih.gov/pubmed/35414722
http://dx.doi.org/10.32074/1591-951X-747
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author Fusco, Nicola
Rizzo, Antonio
Costarelli, Leopoldo
Santinelli, Alfredo
Cerbelli, Bruna
Scatena, Cristian
Macrì, Ettore
Pietribiasi, Francesca
d’Amati, Giulia
Sapino, Anna
Castellano, Isabella
author_facet Fusco, Nicola
Rizzo, Antonio
Costarelli, Leopoldo
Santinelli, Alfredo
Cerbelli, Bruna
Scatena, Cristian
Macrì, Ettore
Pietribiasi, Francesca
d’Amati, Giulia
Sapino, Anna
Castellano, Isabella
author_sort Fusco, Nicola
collection PubMed
description Neoadjuvant therapy (NAT) in breast cancer is administered to downstage the tumor, de-escalate surgery, and provide prognostic information that can be used to tailor subsequent adjuvant therapy. In this respect, the pathological evaluation of both pre-NAT biopsies and post-NAT surgical specimens is crucial to precisely assess the treatment response. With the increasing possibilities of NAT protocols and the rising number of eligible patients, it has become extremely important to standardize the pathological response assessment. Here, we provide an update on the recommendations of the Italian Group for the Study of Breast Pathology - the Italian Society of Pathology (GIPaM-SIAPeC) for the analysis of breast cancer samples before and after NAT.
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spelling pubmed-92482462022-07-13 Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC) Fusco, Nicola Rizzo, Antonio Costarelli, Leopoldo Santinelli, Alfredo Cerbelli, Bruna Scatena, Cristian Macrì, Ettore Pietribiasi, Francesca d’Amati, Giulia Sapino, Anna Castellano, Isabella Pathologica Guidelines Neoadjuvant therapy (NAT) in breast cancer is administered to downstage the tumor, de-escalate surgery, and provide prognostic information that can be used to tailor subsequent adjuvant therapy. In this respect, the pathological evaluation of both pre-NAT biopsies and post-NAT surgical specimens is crucial to precisely assess the treatment response. With the increasing possibilities of NAT protocols and the rising number of eligible patients, it has become extremely important to standardize the pathological response assessment. Here, we provide an update on the recommendations of the Italian Group for the Study of Breast Pathology - the Italian Society of Pathology (GIPaM-SIAPeC) for the analysis of breast cancer samples before and after NAT. Pacini Editore srl 2022-04-01 /pmc/articles/PMC9248246/ /pubmed/35414722 http://dx.doi.org/10.32074/1591-951X-747 Text en © 2022 Copyright by Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access journal distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license: the work can be used by mentioning the author and the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Guidelines
Fusco, Nicola
Rizzo, Antonio
Costarelli, Leopoldo
Santinelli, Alfredo
Cerbelli, Bruna
Scatena, Cristian
Macrì, Ettore
Pietribiasi, Francesca
d’Amati, Giulia
Sapino, Anna
Castellano, Isabella
Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title_full Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title_fullStr Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title_full_unstemmed Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title_short Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
title_sort pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the italian group for the study of breast pathology - italian society of pathology (gipam-siapec)
topic Guidelines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248246/
https://www.ncbi.nlm.nih.gov/pubmed/35414722
http://dx.doi.org/10.32074/1591-951X-747
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