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UVB-Induced Skin Autoinflammation Due to Nlrp1b Mutation and Its Inhibition by Anti-IL-1β Antibody

NLRP1 (NACHT and leucine-rich repeat-containing protein family, pyrin domain-containing protein 1) is an innate immune sensor that is involved in the formation of inflammasome complexes. NLRP1 hyperactivity has been reported to cause inherited autoinflammatory diseases including familial keratosis l...

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Detalles Bibliográficos
Autores principales:	Murase, Yuya, Takeichi, Takuya, Koseki, Jun, Miyasaka, Yuki, Muro, Yoshinao, Ohno, Tamio, Shimamura, Teppei, Akiyama, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248282/ https://www.ncbi.nlm.nih.gov/pubmed/35784371 http://dx.doi.org/10.3389/fimmu.2022.876390

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