Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo

Immunoglobulin E (IgE) antibody is a critical effector molecule for adaptive allergen-induced immune responses, which affect up to 40% of the population worldwide. Allergens are usually innocuous molecules but induce IgE antibody production in allergic subjects. Allergen cross-linking of IgE bound t...

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Detalles Bibliográficos
Autores principales: Khatri, Kriti, Richardson, Crystal M, Glesner, Jill, Kapingidza, Anyway Brenda, Mueller, Geoffrey A, Zhang, Jian, Dolamore, Cole, Vailes, Lisa D, Wünschmann, Sabina, Peebles, R Stokes, Chapman, Martin D, Smith, Scott A, Chruszcz, Maksymilian, Pomés, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248284/
https://www.ncbi.nlm.nih.gov/pubmed/35799831
http://dx.doi.org/10.1093/pnasnexus/pgac054

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