Pick the best of both glucose and lipid metabolism

Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinic...

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Detalles Bibliográficos
Autores principales: Shimizu, Tatsunori, Takahashi, Yuya, Fujita, Hiroki, Waki, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248427/
https://www.ncbi.nlm.nih.gov/pubmed/35212158
http://dx.doi.org/10.1111/jdi.13774
Descripción
Sumario:Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinical benefits in the treatment of diabetes.[Image: see text]

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