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Pick the best of both glucose and lipid metabolism
Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248427/ https://www.ncbi.nlm.nih.gov/pubmed/35212158 http://dx.doi.org/10.1111/jdi.13774 |
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author | Shimizu, Tatsunori Takahashi, Yuya Fujita, Hiroki Waki, Hironori |
author_facet | Shimizu, Tatsunori Takahashi, Yuya Fujita, Hiroki Waki, Hironori |
author_sort | Shimizu, Tatsunori |
collection | PubMed |
description | Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinical benefits in the treatment of diabetes.[Image: see text] |
format | Online Article Text |
id | pubmed-9248427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92484272022-07-05 Pick the best of both glucose and lipid metabolism Shimizu, Tatsunori Takahashi, Yuya Fujita, Hiroki Waki, Hironori J Diabetes Investig Commentaries Isthmin‐1 is an adipokine that has a potent glucose‐lowering effect by stimulating a common intracellular signaling pathway with insulin through a distinct receptor and has an inhibitory effect on lipogenesis in the liver, whereas insulin has the opposite effect. Isthmin‐1 is expected to have clinical benefits in the treatment of diabetes.[Image: see text] John Wiley and Sons Inc. 2022-03-08 2022-07 /pmc/articles/PMC9248427/ /pubmed/35212158 http://dx.doi.org/10.1111/jdi.13774 Text en © 2022 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Commentaries Shimizu, Tatsunori Takahashi, Yuya Fujita, Hiroki Waki, Hironori Pick the best of both glucose and lipid metabolism |
title | Pick the best of both glucose and lipid metabolism |
title_full | Pick the best of both glucose and lipid metabolism |
title_fullStr | Pick the best of both glucose and lipid metabolism |
title_full_unstemmed | Pick the best of both glucose and lipid metabolism |
title_short | Pick the best of both glucose and lipid metabolism |
title_sort | pick the best of both glucose and lipid metabolism |
topic | Commentaries |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248427/ https://www.ncbi.nlm.nih.gov/pubmed/35212158 http://dx.doi.org/10.1111/jdi.13774 |
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