Identification of New Antibodies Targeting Malignant Plasma Cells for Immunotherapy by Next-Generation Sequencing-Assisted Phage Display

To identify new antibodies for the treatment of plasma cell disorders including multiple myeloma (MM), a single-chain Fragment variable (scFv) antibody library was generated by immunizing mice with patient-derived malignant plasma cells. To enrich antibodies binding myeloma antigens, phage display w...

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Detalles Bibliográficos
Autores principales: Krohn, Steffen, Boje, Ammelie Svea, Gehlert, Carina Lynn, Lutz, Sebastian, Darzentas, Nikos, Knecht, Henrik, Herrmann, Dietrich, Brüggemann, Monika, Scheidig, Axel J., Weisel, Katja, Gramatzki, Martin, Peipp, Matthias, Klausz, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248769/
https://www.ncbi.nlm.nih.gov/pubmed/35784366
http://dx.doi.org/10.3389/fimmu.2022.908093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9248769/
https://www.ncbi.nlm.nih.gov/pubmed/35784366
http://dx.doi.org/10.3389/fimmu.2022.908093

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