Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge

Pulmonary tuberculosis (TB) is highly prevalent in Pakistan, and immunosuppressed individuals (including those on long-term corticosteroid therapy) are at an especially high risk of infection. Owing to the limited number of effective antituberculous drugs, treating resistant cases or patients who de...

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Autores principales: Shafique, Mudassir, Tameez-ud-din, Ahsan, Tameez Ud Din, Asim, Chaudhary, Farooq Mohyud Din, Bhatti, Awais A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249006/
https://www.ncbi.nlm.nih.gov/pubmed/35785003
http://dx.doi.org/10.7759/cureus.25557
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author Shafique, Mudassir
Tameez-ud-din, Ahsan
Tameez Ud Din, Asim
Chaudhary, Farooq Mohyud Din
Bhatti, Awais A
author_facet Shafique, Mudassir
Tameez-ud-din, Ahsan
Tameez Ud Din, Asim
Chaudhary, Farooq Mohyud Din
Bhatti, Awais A
author_sort Shafique, Mudassir
collection PubMed
description Pulmonary tuberculosis (TB) is highly prevalent in Pakistan, and immunosuppressed individuals (including those on long-term corticosteroid therapy) are at an especially high risk of infection. Owing to the limited number of effective antituberculous drugs, treating resistant cases or patients who develop unfavorable side effects from the first-line agents becomes a daunting task. We discuss a patient with congenital adrenal hyperplasia (CAH) suffering from pulmonary TB who developed drug-induced hepatitis after being started on recommended first-line anti-TB drugs.
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spelling pubmed-92490062022-07-02 Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge Shafique, Mudassir Tameez-ud-din, Ahsan Tameez Ud Din, Asim Chaudhary, Farooq Mohyud Din Bhatti, Awais A Cureus Internal Medicine Pulmonary tuberculosis (TB) is highly prevalent in Pakistan, and immunosuppressed individuals (including those on long-term corticosteroid therapy) are at an especially high risk of infection. Owing to the limited number of effective antituberculous drugs, treating resistant cases or patients who develop unfavorable side effects from the first-line agents becomes a daunting task. We discuss a patient with congenital adrenal hyperplasia (CAH) suffering from pulmonary TB who developed drug-induced hepatitis after being started on recommended first-line anti-TB drugs. Cureus 2022-06-01 /pmc/articles/PMC9249006/ /pubmed/35785003 http://dx.doi.org/10.7759/cureus.25557 Text en Copyright © 2022, Shafique et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Shafique, Mudassir
Tameez-ud-din, Ahsan
Tameez Ud Din, Asim
Chaudhary, Farooq Mohyud Din
Bhatti, Awais A
Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title_full Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title_fullStr Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title_full_unstemmed Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title_short Antituberculous Drug-Induced Hepatitis in a Patient With Congenital Adrenal Hyperplasia: A Clinical Challenge
title_sort antituberculous drug-induced hepatitis in a patient with congenital adrenal hyperplasia: a clinical challenge
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249006/
https://www.ncbi.nlm.nih.gov/pubmed/35785003
http://dx.doi.org/10.7759/cureus.25557
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