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Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension
Severe pulmonary arterial hypertension (PAH) is associated with high morbidity and mortality. Therapeutic approaches for intermediate- and high-risk pulmonary arterial hypertension have now shifted toward initial combination management, often including parenteral epoprostenol and iloprost and early...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249055/ https://www.ncbi.nlm.nih.gov/pubmed/35783883 http://dx.doi.org/10.7759/cureus.25552 |
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author | Murali, Sindhubarathi Khanal, Subrat Banerjee, Sanchari Christie, Omari Ramakrishna, Kartik |
author_facet | Murali, Sindhubarathi Khanal, Subrat Banerjee, Sanchari Christie, Omari Ramakrishna, Kartik |
author_sort | Murali, Sindhubarathi |
collection | PubMed |
description | Severe pulmonary arterial hypertension (PAH) is associated with high morbidity and mortality. Therapeutic approaches for intermediate- and high-risk pulmonary arterial hypertension have now shifted toward initial combination management, often including parenteral epoprostenol and iloprost and early assessment for a lung transplant. After the initiation of therapy, usually various combinations of different classes of medication, it is important to consider the potential interruption in therapy causing rebound PAH. We present two patients recently admitted to our hospital with rebound symptoms after interruption of their pulmonary vasodilator therapy. |
format | Online Article Text |
id | pubmed-9249055 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-92490552022-07-02 Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension Murali, Sindhubarathi Khanal, Subrat Banerjee, Sanchari Christie, Omari Ramakrishna, Kartik Cureus Internal Medicine Severe pulmonary arterial hypertension (PAH) is associated with high morbidity and mortality. Therapeutic approaches for intermediate- and high-risk pulmonary arterial hypertension have now shifted toward initial combination management, often including parenteral epoprostenol and iloprost and early assessment for a lung transplant. After the initiation of therapy, usually various combinations of different classes of medication, it is important to consider the potential interruption in therapy causing rebound PAH. We present two patients recently admitted to our hospital with rebound symptoms after interruption of their pulmonary vasodilator therapy. Cureus 2022-05-31 /pmc/articles/PMC9249055/ /pubmed/35783883 http://dx.doi.org/10.7759/cureus.25552 Text en Copyright © 2022, Murali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Murali, Sindhubarathi Khanal, Subrat Banerjee, Sanchari Christie, Omari Ramakrishna, Kartik Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title | Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title_full | Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title_fullStr | Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title_full_unstemmed | Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title_short | Pause at Your Own Peril: A Case Series on Rebound Pulmonary Hypertension |
title_sort | pause at your own peril: a case series on rebound pulmonary hypertension |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249055/ https://www.ncbi.nlm.nih.gov/pubmed/35783883 http://dx.doi.org/10.7759/cureus.25552 |
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