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Evaluation of genetic polymorphism of CYP3A5 in normal healthy participants from western India - A cross-sectional study

BACKGROUND: CYP3A5 enzymes belong to the phase I Group of drug-metabolizing enzymes, which are involved in the metabolism of 50% of the drugs. Participants with CYP3A5 genotype: CYP3A5 *1/*1 are fast metabolizers of drugs and hence will require higher dosing. Whereas those with CYP3A5 * 3/*3 are poo...

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Detalles Bibliográficos
Autores principales: Maurya, Miteshkumar Rajaram, Gautam, Sunanda, Raj, Jeffrey Pradeep, Saha, Shruti, Ambre, Sanchita, Thakurdesai, Aishwarya, Shah, Aditya, Thatte, Urmila Mukund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249149/
https://www.ncbi.nlm.nih.gov/pubmed/35546460
http://dx.doi.org/10.4103/ijp.ijp_279_21

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