Animal models - Mimicking the pain of trigeminal neuralgia

Trigeminal neuralgia (TN) is an episodic facial pain which feels like an electric shock of unilateral origin. This neuropathic disorder is an intensely stressful to bear for patient and impacts the quality of life. Most of the cases of TN arise when the root of fifth cranial nerve, i.e., trigeminal...

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Autores principales: Gupta, Sonu, Bansal, Ravinder Nath, Sodhi, Surender Pal Singh, Brar, Gursimrat Kaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249160/
https://www.ncbi.nlm.nih.gov/pubmed/35546466
http://dx.doi.org/10.4103/ijp.ijp_296_19
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author Gupta, Sonu
Bansal, Ravinder Nath
Sodhi, Surender Pal Singh
Brar, Gursimrat Kaur
author_facet Gupta, Sonu
Bansal, Ravinder Nath
Sodhi, Surender Pal Singh
Brar, Gursimrat Kaur
author_sort Gupta, Sonu
collection PubMed
description Trigeminal neuralgia (TN) is an episodic facial pain which feels like an electric shock of unilateral origin. This neuropathic disorder is an intensely stressful to bear for patient and impacts the quality of life. Most of the cases of TN arise when the root of fifth cranial nerve, i.e., trigeminal nerve is compressed after a few millimeters of its entry into the pons. This article describes various animal models and the role of biomarkers to study the underlying mechanisms of neuropathic pain in animal models as well as different modes of management of TN.
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spelling pubmed-92491602022-07-02 Animal models - Mimicking the pain of trigeminal neuralgia Gupta, Sonu Bansal, Ravinder Nath Sodhi, Surender Pal Singh Brar, Gursimrat Kaur Indian J Pharmacol Review Article Trigeminal neuralgia (TN) is an episodic facial pain which feels like an electric shock of unilateral origin. This neuropathic disorder is an intensely stressful to bear for patient and impacts the quality of life. Most of the cases of TN arise when the root of fifth cranial nerve, i.e., trigeminal nerve is compressed after a few millimeters of its entry into the pons. This article describes various animal models and the role of biomarkers to study the underlying mechanisms of neuropathic pain in animal models as well as different modes of management of TN. Wolters Kluwer - Medknow 2022 2022-05-10 /pmc/articles/PMC9249160/ /pubmed/35546466 http://dx.doi.org/10.4103/ijp.ijp_296_19 Text en Copyright: © 2022 Indian Journal of Pharmacology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Gupta, Sonu
Bansal, Ravinder Nath
Sodhi, Surender Pal Singh
Brar, Gursimrat Kaur
Animal models - Mimicking the pain of trigeminal neuralgia
title Animal models - Mimicking the pain of trigeminal neuralgia
title_full Animal models - Mimicking the pain of trigeminal neuralgia
title_fullStr Animal models - Mimicking the pain of trigeminal neuralgia
title_full_unstemmed Animal models - Mimicking the pain of trigeminal neuralgia
title_short Animal models - Mimicking the pain of trigeminal neuralgia
title_sort animal models - mimicking the pain of trigeminal neuralgia
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249160/
https://www.ncbi.nlm.nih.gov/pubmed/35546466
http://dx.doi.org/10.4103/ijp.ijp_296_19
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