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The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability

Aneuploidy and chromosomal instability are both commonly found in cancer. Chromosomal instability leads to karyotype heterogeneity in tumors and is associated with therapy resistance, metastasis and poor prognosis. It has been hypothesized that aneuploidy per se is sufficient to drive CIN, however d...

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Detalles Bibliográficos
Autores principales:	Hintzen, Dorine C., Soto, Mar, Schubert, Michael, Bakker, Bjorn, Spierings, Diana C. J., Szuhai, Karoly, Lansdorp, Peter M., Kluin, Roel J. C., Foijer, Floris, Medema, René H., Raaijmakers, Jonne A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249180/ https://www.ncbi.nlm.nih.gov/pubmed/35776704 http://dx.doi.org/10.1371/journal.pone.0268579

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