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A structured model and likelihood approach to estimate yeast prion propagon replication rates and their asymmetric transmission
Prion proteins cause a variety of fatal neurodegenerative diseases in mammals but are generally harmless to Baker’s yeast (Saccharomyces cerevisiae). This makes yeast an ideal model organism for investigating the protein dynamics associated with these diseases. The rate of disease onset is related t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249220/ https://www.ncbi.nlm.nih.gov/pubmed/35776712 http://dx.doi.org/10.1371/journal.pcbi.1010107 |