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Fish female-biased gene cyp19a1a leads to female antiviral response attenuation between sexes by autophagic degradation of MITA

From insects to mammals, both innate and adaptive immune response are usually higher in females than in males, with the sex chromosome and hormonal differences considered the main reasons. Here, we report that zebrafish cyp19a1a (cytochrome P450, family 19, subfamily A, polypeptide 1a), an autosomal...

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Detalles Bibliográficos
Autores principales:	Lu, Long-Feng, Jiang, Jing-Yu, Du, Wen-Xuan, Wang, Xue-Li, Li, Zhuo-Cong, Zhou, Xiao-Yu, Zhang, Can, Mou, Cheng-Yan, Chen, Dan-Dan, Li, Zhi, Zhou, Li, Gui, Jian-Fang, Li, Xi-Yin, Li, Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249237/ https://www.ncbi.nlm.nih.gov/pubmed/35727817 http://dx.doi.org/10.1371/journal.ppat.1010626

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