Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8(+) T cell response during acute and chronic toxoplasmosis

Initial TCR engagement (priming) of naive CD8(+) T cells results in T cell expansion, and these early events influence the generation of diverse effector and memory populations. During infection, activated T cells can re-encounter cognate antigen, but how these events influence local effector respon...

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Detalles Bibliográficos
Autores principales: Shallberg, Lindsey A., Phan, Anthony T., Christian, David A., Perry, Joseph A., Haskins, Breanne E., Beiting, Daniel P., Harris, Tajie H., Koshy, Anita A., Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249239/
https://www.ncbi.nlm.nih.gov/pubmed/35727849
http://dx.doi.org/10.1371/journal.ppat.1010296

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