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Alzheimer’s Amyloid-β Accelerates Human Neuronal Cell Senescence Which Could Be Rescued by Sirtuin-1 and Aspirin
Cellular senescence is a major biological process related to aging. Neuronal cell senescence contributes to the pathogenesis of many aging-related neurodegenerative diseases including Alzheimer’s disease (AD). In this study, we showed that amyloid-β(42) oligomers (Aβ), one of the core pathological p...
Autores principales: | Li, Yi, Lu, Juan, Hou, Yujun, Huang, Shichao, Pei, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249263/ https://www.ncbi.nlm.nih.gov/pubmed/35783098 http://dx.doi.org/10.3389/fncel.2022.906270 |
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