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Alzheimer’s Amyloid-β Accelerates Human Neuronal Cell Senescence Which Could Be Rescued by Sirtuin-1 and Aspirin

Cellular senescence is a major biological process related to aging. Neuronal cell senescence contributes to the pathogenesis of many aging-related neurodegenerative diseases including Alzheimer’s disease (AD). In this study, we showed that amyloid-β(42) oligomers (Aβ), one of the core pathological p...

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Detalles Bibliográficos
Autores principales: Li, Yi, Lu, Juan, Hou, Yujun, Huang, Shichao, Pei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249263/
https://www.ncbi.nlm.nih.gov/pubmed/35783098
http://dx.doi.org/10.3389/fncel.2022.906270

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