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Aspalathus linearis suppresses cell survival and proliferation of enzalutamide-resistant prostate cancer cells via inhibition of c-Myc and stability of androgen receptor

Enzalutamide, a nonsteroidal antiandrogen, significantly prolonged the survival of patients with metastatic castration-resistant prostate cancer (CRPC). However, patients receiving enzalutamide frequently develop drug resistance. Rooibos (Aspalathus linearis) is a shrub-like leguminous fynbos plant...

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Detalles Bibliográficos
Autores principales:	Wang, Bi-Juan, Huang, Shih-Han, Kao, Cheng-Li, Muller, Christo J. F., Wang, Ya-Pei, Chang, Kai-Hsiung, Wen, Hui-Chin, Yeh, Chien-Chih, Shih, Li-Jane, Kao, Yung-Hsi, Huang, Shu-Pin, Li, Chia-Yang, Chuu, Chih-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249401/ https://www.ncbi.nlm.nih.gov/pubmed/35776912 http://dx.doi.org/10.1371/journal.pone.0270803

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