Cargando…

Protective Effect of Hedyotis diffusa Willd. Ethanol Extract on Isoniazid-Induced Liver Injury in the Zebrafish Model

OBJECTIVE: This study aims to investigate the hepatoprotective effect and molecular mechanism of Hedyotis diffusa Willd. ethanol extract (HDWE) against isoniazid (INH)-induced liver injury in the zebrafish model. METHODS: INH-induced liver injury model was established by adding an immersion bath of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xin, Zhao, Jie, Zhang, Rui, Liu, Xinlu, Ma, Chuanjiang, Cao, Guangshang, Wei, Yongli, Yang, Peimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249440/ https://www.ncbi.nlm.nih.gov/pubmed/35783199 http://dx.doi.org/10.2147/DDDT.S358498

Ejemplares similares

The Antitumor Constituents from Hedyotis Diffusa Willd
por: Wang, Changfu, et al.
Publicado: (2017)

Molecular Mechanism of Anti-Colorectal Cancer Effect of Hedyotis diffusa Willd and Its Extracts
por: Wu, Zihong, et al.
Publicado: (2022)

The Hedyotis diffusa Willd. (Rubiaceae): A Review on Phytochemistry, Pharmacology, Quality Control and Pharmacokinetics
por: Chen, Rui, et al.
Publicado: (2016)

Chemical Profiles and Protective Effect of Hedyotis diffusa Willd in Lipopolysaccharide-Induced Renal Inflammation Mice
por: Ye, Jian-Hong, et al.
Publicado: (2015)

Exploring the mechanism of action of Hedyotis diffusa Willd on acne using network analysis
por: Seo, Gwangyeel, et al.
Publicado: (2023)

Network Pharmacology Analysis and Experimental Verification on Antiangiogenesis Mechanism of Hedyotis diffusa Willd in Liver Cancer
por: Wu, Hongyan, et al.
Publicado: (2023)

The protective capability of Hedyotis diffusa Willd on lupus nephritis by attenuating the IL-17 expression in MRL/lpr mice
por: Li, Ying, et al.
Publicado: (2022)

Therapeutic effects of Hedyotis diffusa Willd in a COPD mouse model challenged with LPS and smoke
por: Liu, Renping, et al.
Publicado: (2018)

A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer
por: Liu, Xinkui, et al.
Publicado: (2018)

Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer
por: Liu, Xinkui, et al.
Publicado: (2018)

Hedyotis diffusa Willd. Suppresses Hepatocellular Carcinoma via Downregulating AKT/mTOR Pathways
por: Huang, Lingli, et al.
Publicado: (2021)

Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells
por: Wu, Kenan, et al.
Publicado: (2022)

Synergistic inhibition of leukemia WEHI-3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo
por: Kuo, Yu-Jui, et al.
Publicado: (2017)

Network pharmacology and experimental validation to identify the potential mechanism of Hedyotis diffusa Willd against rheumatoid arthritis
por: Deng, Hui, et al.
Publicado: (2023)

Hedyotis diffusa Willd Inhibits Colorectal Cancer Growth in Vivo via Inhibition of STAT3 Signaling Pathway
por: Cai, Qiaoyan, et al.
Publicado: (2012)

Mechanism of Hedyotis Diffusa in the Treatment of Cervical Cancer
por: Qian, Kai, et al.
Publicado: (2021)

Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells
por: Ning, Weimin, et al.
Publicado: (2022)

Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach
por: Song, Yanan, et al.
Publicado: (2019)

Chemical Constituents of Hedyotis diffusa and Their Anti-Inflammatory Bioactivities
por: Hung, Hsin-Yi, et al.
Publicado: (2022)

Hedyotis diffusa Willd. extract suppresses proliferation and induces apoptosis via IL-6-inducible STAT3 pathway inactivation in human colorectal cancer cells
por: LIN, JIUMAO, et al.
Publicado: (2015)

Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis
por: Wang, Yaru, et al.
Publicado: (2018)

Metabolic regulations of a decoction of Hedyotis diffusa in acute liver injury of mouse models
por: Dai, Min, et al.
Publicado: (2017)

Preclinical Pharmacokinetic Interaction and Histopathological Analyses of Hedyotis diffusa on Sorafenib in Rats
por: Ting, Chin-Tsung, et al.
Publicado: (2021)

Differentiation of Hedyotis diffusa and Common Adulterants Based on Chloroplast Genome Sequencing and DNA Barcoding Markers
por: Yik, Mavis Hong-Yu, et al.
Publicado: (2021)

Molecular mechanism of Hedyotis Diffusae Herba in the treatment of lupus nephritis based on network pharmacology
por: Yang, Jinfei, et al.
Publicado: (2023)

Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of Hedyotis Diffusa Willd against HepG2 Carcinoma Cells Mediated via Apoptosis
por: Li, Yun-lan, et al.
Publicado: (2016)

Determination of Oleanolic and Ursolic Acids in Hedyotis diffusa Using Hyphenated Ultrasound-Assisted Supercritical Carbon Dioxide Extraction and Chromatography
por: Wei, Ming-Chi, et al.
Publicado: (2015)

Effect of whole plant of Rostellularia diffusa Willd. on experimental stress in mice
por: Nagasirisha, Mandipati, et al.
Publicado: (2014)

Mitigation of Aflatoxin B(1) Hepatoxicity by Dietary Hedyotis diffusa Is Associated with Activation of NRF2/ARE Signaling in Chicks
por: Zhao, Ling, et al.
Publicado: (2021)

Phytochemical analysis of hydroethanolic extract of Turnera diffusa Willd and evaluation of its effects on astrocyte cell death
por: Bezerra, Andréia Gomes, et al.
Publicado: (2016)

Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria
por: Ji, Shaojian, et al.
Publicado: (2017)

Ethanol Extract of Oldenlandia diffusa – an Effective Chemotherapeutic for the Treatment of Colorectal Cancer in Humans: -Anti-Cancer Effects of Oldenlandia diffusa-
por: Lee, Soojin, et al.
Publicado: (2016)

Bioassay-Guided Isolation of Anti-Alzheimer Active Components from the Aerial Parts of Hedyotis diffusa and Simultaneous Analysis for Marker Compounds
por: Park, Jun Hee, et al.
Publicado: (2020)

Novel Antiviral Efficacy of Hedyotis diffusa and Artemisia capillaris Extracts against Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Infection and Immunoregulatory Cytokine Signatures
por: Mao, Zhan Qiu, et al.
Publicado: (2022)

Molecular Targets and Mechanisms of Hedyotis diffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking
por: Yang, Zhenpeng, et al.
Publicado: (2022)

Hedyotis diffusa Combined with Scutellaria barbata Are the Core Treatment of Chinese Herbal Medicine Used for Breast Cancer Patients: A Population-Based Study
por: Yeh, Yuan-Chieh, et al.
Publicado: (2014)

Seed morphology and germination of <Turnera diffusa> Willd. ex Schult. emulating environmental conditions within ant nest
por: Puga-Guzmán, Paola Scarlet, et al.
Publicado: (2023)

Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression
por: Pan, Li-Tao, et al.
Publicado: (2016)

Ethyl Acetate Fraction from Hedyotis diffusa plus Scutellaria barbata Exerts Anti-Inflammatory Effects by Regulating miR-155 Expression and JNK Signaling Pathway
por: Xu, Yuan, et al.
Publicado: (2018)

Hedyotis diffusa plus Scutellaria barbata Suppress the Growth of Non-Small-Cell Lung Cancer via NLRP3/NF-κB/MAPK Signaling Pathways
por: Lv, Ya-Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_doivgus1u55b21c06u5sn245gg