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Inhibition of PLK3 Attenuates Tubular Epithelial Cell Apoptosis after Renal Ischemia–Reperfusion Injury by Blocking the ATM/P53-Mediated DNA Damage Response

OBJECTIVE: Renal ischemia–reperfusion (I/R) injury is a major cause of acute kidney injury (AKI) in transplanted kidneys. This study was aimed at exploring the role of PLK3 (polo-like kinase 3) in renal I/R injury, focusing on its relationship with oxidative stress-induced DNA damage and renal tubul...

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Detalles Bibliográficos
Autores principales:	Deng, Weiming, Wei, Xiangling, Xie, Zhenwei, Zhang, Rui, Dong, Zhanwen, Zhang, Jinhua, Luo, You, Cheng, Qingdi, Wang, Ruojiao, Li, Heng, Na, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249506/ https://www.ncbi.nlm.nih.gov/pubmed/35783188 http://dx.doi.org/10.1155/2022/4201287

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