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Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction

A porous material is considered to be a potential material that can be used to repair bone defects. However, the methods of designing of a highly porous structure within the allowable stress range remain to be researched. Therefore, this study was aimed at presenting a method for generating a three-...

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Autores principales: Liu, Renshun, Su, Yuxiong, Yang, Weifa, Dang, Xiaobing, Zhang, Chunyu, Du, Ruxu, Zhong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249542/
https://www.ncbi.nlm.nih.gov/pubmed/35782881
http://dx.doi.org/10.1155/2022/8686670
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author Liu, Renshun
Su, Yuxiong
Yang, Weifa
Dang, Xiaobing
Zhang, Chunyu
Du, Ruxu
Zhong, Yong
author_facet Liu, Renshun
Su, Yuxiong
Yang, Weifa
Dang, Xiaobing
Zhang, Chunyu
Du, Ruxu
Zhong, Yong
author_sort Liu, Renshun
collection PubMed
description A porous material is considered to be a potential material that can be used to repair bone defects. However, the methods of designing of a highly porous structure within the allowable stress range remain to be researched. Therefore, this study was aimed at presenting a method for generating a three-dimensional tetrahedral porous structure characterized by low peak stress and high porosity for the reconstruction of mandibular defects. Firstly, the initial tetrahedral porous structure was fabricated with the strut diameters set to 0.4 mm and a mean cell size of 2.4 mm in the design model space. Following this, the simulation analysis was carried out. Further, a homogenization algorithm was used for homogenizing the stress distribution, increasing porosity, and controlling peak stress of the porous structure by adjusting the strut diameters. The results showed that compared with the initial porous structure, the position of the large stress regions remained unchanged, and the peak stress fluctuated slightly in the mandible and fixation system with the optimized porous structure under two occlusions. The optimized porous structure had a higher porosity and more uniform stress distribution, and the maximum stress was lower than the target stress value. The design and optimization technique of the porous structure presented in this paper can be used to control peak stress, improve porosity, and fabricate a lightweight scaffold, which provides a potential solution for mandibular reconstruction.
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spelling pubmed-92495422022-07-02 Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction Liu, Renshun Su, Yuxiong Yang, Weifa Dang, Xiaobing Zhang, Chunyu Du, Ruxu Zhong, Yong Appl Bionics Biomech Research Article A porous material is considered to be a potential material that can be used to repair bone defects. However, the methods of designing of a highly porous structure within the allowable stress range remain to be researched. Therefore, this study was aimed at presenting a method for generating a three-dimensional tetrahedral porous structure characterized by low peak stress and high porosity for the reconstruction of mandibular defects. Firstly, the initial tetrahedral porous structure was fabricated with the strut diameters set to 0.4 mm and a mean cell size of 2.4 mm in the design model space. Following this, the simulation analysis was carried out. Further, a homogenization algorithm was used for homogenizing the stress distribution, increasing porosity, and controlling peak stress of the porous structure by adjusting the strut diameters. The results showed that compared with the initial porous structure, the position of the large stress regions remained unchanged, and the peak stress fluctuated slightly in the mandible and fixation system with the optimized porous structure under two occlusions. The optimized porous structure had a higher porosity and more uniform stress distribution, and the maximum stress was lower than the target stress value. The design and optimization technique of the porous structure presented in this paper can be used to control peak stress, improve porosity, and fabricate a lightweight scaffold, which provides a potential solution for mandibular reconstruction. Hindawi 2022-06-24 /pmc/articles/PMC9249542/ /pubmed/35782881 http://dx.doi.org/10.1155/2022/8686670 Text en Copyright © 2022 Renshun Liu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liu, Renshun
Su, Yuxiong
Yang, Weifa
Dang, Xiaobing
Zhang, Chunyu
Du, Ruxu
Zhong, Yong
Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title_full Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title_fullStr Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title_full_unstemmed Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title_short Novel Design and Optimization of Porous Titanium Structure for Mandibular Reconstruction
title_sort novel design and optimization of porous titanium structure for mandibular reconstruction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249542/
https://www.ncbi.nlm.nih.gov/pubmed/35782881
http://dx.doi.org/10.1155/2022/8686670
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