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Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B

Protein tyrosine phosphatase 1B (PTP1B), a negative regulator of the insulin signaling pathway, has gained attention as a validated druggable target in the management of type 2 diabetes mellitus (T2DM). The lack of clinically approved PTP1B inhibitors has continued to prompt research in plant-derive...

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Detalles Bibliográficos
Autores principales: Rampadarath, Athika, Balogun, Fatai Oladunni, Pillay, Charlene, Sabiu, Saheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249544/
https://www.ncbi.nlm.nih.gov/pubmed/35782627
http://dx.doi.org/10.1155/2022/6233217