Potential intravenous immunoglobulin-induced optic disc edema

PURPOSE: To report a case of recurrent and bilateral optic disc edema following intravenous immunoglobulin (IVIG) administration. OBSERVATIONS: A 46 year-old woman received IVIG on 3 separate occasions over 7 years for Non-Hodgkin's Lymphoma (NHL) and each time developed headaches and transient...

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Detalles Bibliográficos
Autores principales: Britton, Anna K., Vaze, Anagha, Milliken, Sam, Fraser, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249594/
https://www.ncbi.nlm.nih.gov/pubmed/35789798
http://dx.doi.org/10.1016/j.ajoc.2022.101617
Descripción
Sumario:PURPOSE: To report a case of recurrent and bilateral optic disc edema following intravenous immunoglobulin (IVIG) administration. OBSERVATIONS: A 46 year-old woman received IVIG on 3 separate occasions over 7 years for Non-Hodgkin's Lymphoma (NHL) and each time developed headaches and transient visual disturbance, and was subsequently found to have bilateral optic disc swelling. Lumbar puncture confirmed raised cerebrospinal fluid (CSF) opening pressure and there was resolution following treatment with oral acetazolamide (Diamox). CONCLUSIONS AND IMPORTANCE: To our knowledge there is no literature on papilledema following administration of IVIG. This case is pertinent for physicians treating patients with IVIG who develop headache, transient visual disturbance and optic disc edema.

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