Cargando…

Efficacy of cabozantinib therapy for brain metastases from renal cell carcinoma

INTRODUCTION: We report two cases of renal cell carcinoma with brain metastases that showed remarkable responses to cabozantinib. CASE PRESENTATION: (Case 1) A 70‐year‐old man with cT3aN0M0 clear cell renal cell carcinoma underwent radical nephrectomy and developed multiple brain metastases 2 months...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakagawa, Takashi, Kijima, Toshiki, Imasato, Naoki, Nagoshi, Akihiko, Nakamura, Gaku, Uematsu, Toshitaka, Suzuki, Issei, Nishihara, Daisaku, Kamai, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Case Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249636/ https://www.ncbi.nlm.nih.gov/pubmed/35795125 http://dx.doi.org/10.1002/iju5.12459

Ejemplares similares

A case of clear cell renal cell carcinoma with vena cava thrombus responding to presurgical avelumab, and axitinib
por: Suzuki, Issei, et al.
Publicado: (2021)

Presurgical avelumab plus axitinib in an immunosenescent octogenarian with renal cell carcinoma invading the vena cava
por: Uematsu, Toshitaka, et al.
Publicado: (2022)

Abdominal wall abscess resembling urachal carcinoma caused by ileal diverticulitis
por: Imasato, Naoki, et al.
Publicado: (2022)

A case of testicular torsion successfully treated with tunica albuginea incision and tunica vaginalis patch
por: Suzuki, Issei, et al.
Publicado: (2023)

Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation
por: Kamai, Takao, et al.
Publicado: (2022)

Increased co-expression of stromal HHLA2 and fibroblast activation protein in upper tract urothelial carcinoma
por: Nishihara, Daisaku, et al.
Publicado: (2023)

Successful management of ureteral injury after gender-affirming laparoscopic hysterectomy: A case report
por: Nakamura, Gaku, et al.
Publicado: (2022)

A case of estrogen‐secreting adrenocortical carcinoma: Comprehensive immunohistochemical analysis of disorganized steroid genesis
por: Yokoyama, Megumi, et al.
Publicado: (2021)

5-Fluorouracil-based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase
por: Narimatsu, Takahiro, et al.
Publicado: (2019)

A case of renal trauma successfully treated by close monitoring of intravesical pressure and subsequent intervention
por: Suzuki, Issei, et al.
Publicado: (2022)

Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients
por: Kijima, Toshiki, et al.
Publicado: (2022)

A case of penile self‐mutilation during a suicidal attempt successfully treated using a multidisciplinary approach
por: Nagoshi, Akihiko, et al.
Publicado: (2022)

Plasma progastrin‐releasing peptide level shows different predictive profiles for treatment response by androgen receptor axis‐targeted agents in patients with metastatic castration‐resistant prostate cancer
por: Yashi, Masahiro, et al.
Publicado: (2022)

Spontaneous regression of multiple pulmonary metastases accompanied by normalization of serum immune markers following cytoreductive nephrectomy in a patient with clear‐cell renal cell carcinoma
por: Okazaki, Akihito, et al.
Publicado: (2020)

A case of self-inserted foreign body in the urinary bladder: Usefulness of three-dimensional reconstruction computed tomography for surgery planning
por: Yokoyama, Megumi, et al.
Publicado: (2022)

Elevated expression of B7 homolog 4 is associated with disease progression in upper urinary tract urothelial carcinoma
por: Mizuno, Tomoya, et al.
Publicado: (2021)

The Predictive Value of Glycated Hemoglobin and Albumin for the Clinical Course Following Hospitalization of Patients with Febrile Urinary Tract Infection
por: Kobayashi, Minoru, et al.
Publicado: (2018)

Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to nivolumab plus ipilimumab
por: Fuchizawa, Hirotaka, et al.
Publicado: (2021)

A case of adrenal undifferentiated pleomorphic sarcoma with tertiary lymphoid structures responded to pembrolizumab
por: Kokubun, Hidetoshi, et al.
Publicado: (2023)

Elevated serum levels of cardiovascular biomarkers are associated with progression of renal cancer
por: Kamai, Takao, et al.
Publicado: (2018)

Prostate-specific antigen kinetics contributes to decision making for biopsy referral: the predictive implication for PSA retest in patients with elevated PSA levels
por: Kobayashi, Minoru, et al.
Publicado: (2023)

Utility of whole‐body diffusion‐weighted magnetic resonance imaging in the management of treatment‐related neuroendocrine prostate cancer
por: Kurashina, Ryo, et al.
Publicado: (2020)

Immunohistochemical expressionof sodium-dependent glucose transporter - 2 (SGLT-2) in clear cell renal carcinoma: possible prognostic implications
por: Kobayashi, Minoru, et al.
Publicado: (2019)

Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma
por: Kamai, Takao, et al.
Publicado: (2022)

Activity of cabozantinib in radioresistant brain metastases from renal cell carcinoma: two case reports
por: Négrier, Sylvie, et al.
Publicado: (2018)

Cabozantinib‐induced renal thrombotic microangiopathy
por: La Manna, Gaetano, et al.
Publicado: (2017)

Increased expression of adenosine 2A receptors in metastatic renal cell carcinoma is associated with poorer response to anti-vascular endothelial growth factor agents and anti-PD-1/Anti-CTLA4 antibodies and shorter survival
por: Kamai, Takao, et al.
Publicado: (2021)

Single nucleotide variants of succinate dehydrogenase A gene in renal cell carcinoma
por: Kamai, Takao, et al.
Publicado: (2021)

A case of perirenal extra-adrenal myelolipoma mimicking liposarcoma
por: Shimoda, Hiroki, et al.
Publicado: (2023)

Extravasation of Urine Associated with Bilateral Complete Ureteral Duplication, Vesicoureteral Reflux and Benign Prostatic Hyperplasia
por: Suzuki, Issei, et al.
Publicado: (2017)

Axitinib for preoperative downstaging of renal cell carcinoma with sarcomatoid differentiation and direct invasion of the duodenum and inferior vena cava: a case report
por: Yuki, Hideo, et al.
Publicado: (2014)

Clinical Significance of Serum Soluble T Cell Regulatory Molecules in Clear Cell Renal Cell Carcinoma
por: Masuda, Akinori, et al.
Publicado: (2014)

Efficacy of Cabozantinib in Metastatic MiT Family Translocation Renal Cell Carcinomas
por: Thouvenin, Jonathan, et al.
Publicado: (2022)

Cabozantinib for the Management of Metastatic Clear Cell Renal Cell Carcinoma
por: Vecchio, Sharon J. Del, et al.
Publicado: (2018)

Cabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell Carcinoma
por: Tannir, Nizar M., et al.
Publicado: (2017)

Increased expression of system large amino acid transporter (LAT)-1 mRNA is associated with invasive potential and unfavorable prognosis of human clear cell renal cell carcinoma
por: Betsunoh, Hironori, et al.
Publicado: (2013)

Cabozantinib in metastatic renal cell carcinoma: latest findings and clinical potential
por: Bersanelli, Melissa, et al.
Publicado: (2017)

Antitumor Effect of Cabozantinib in Bone Metastatic Models of Renal Cell Carcinoma
por: Iuliani, Michele, et al.
Publicado: (2021)

Exposure–response analyses of cabozantinib in patients with metastatic renal cell cancer
por: Krens, Stefanie D., et al.
Publicado: (2022)

Immune cell mediated cabozantinib resistance for patients with renal cell carcinoma
por: Park, Keon Young, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k60mgfihoud4tp4gqaa50kdkdh