Japanese giant benign prostatic hyperplasia: Sibling cases

INTRODUCTION: The pathophysiology of benign prostatic hyperplasia (BPH) remains incompletely understood but is likely multifactorial. Inflammation and metabolic factors may increase the risk of BPH. Several studies have evaluated the possible roles played by genetic factors. Here, we describe two ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohyama, Takehiro, Endo, Fumiyasu, Shimbo, Masaki, Hattori, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249644/
https://www.ncbi.nlm.nih.gov/pubmed/35795106
http://dx.doi.org/10.1002/iju5.12467
_version_ 1784739631146729472
author Ohyama, Takehiro
Endo, Fumiyasu
Shimbo, Masaki
Hattori, Kazunori
author_facet Ohyama, Takehiro
Endo, Fumiyasu
Shimbo, Masaki
Hattori, Kazunori
author_sort Ohyama, Takehiro
collection PubMed
description INTRODUCTION: The pathophysiology of benign prostatic hyperplasia (BPH) remains incompletely understood but is likely multifactorial. Inflammation and metabolic factors may increase the risk of BPH. Several studies have evaluated the possible roles played by genetic factors. Here, we describe two cases of suspected familial BPH. CASE PRESENTATIONS: We report the cases of two brothers, aged 77 and 69 years, with giant BPH. As both exhibited urinary retention, we performed Holmium Laser Enucleation of the Prostate (HoLEP) and obtained tissue samples weighing 276 g and 153 g, respectively. The postoperative courses were good. CONCLUSION: We experienced two cases of sibling BPH with volumes exceeding 200 mL and successfully treated them with HoLEP.
format Online
Article
Text
id pubmed-9249644
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-92496442022-07-05 Japanese giant benign prostatic hyperplasia: Sibling cases Ohyama, Takehiro Endo, Fumiyasu Shimbo, Masaki Hattori, Kazunori IJU Case Rep Case Reports INTRODUCTION: The pathophysiology of benign prostatic hyperplasia (BPH) remains incompletely understood but is likely multifactorial. Inflammation and metabolic factors may increase the risk of BPH. Several studies have evaluated the possible roles played by genetic factors. Here, we describe two cases of suspected familial BPH. CASE PRESENTATIONS: We report the cases of two brothers, aged 77 and 69 years, with giant BPH. As both exhibited urinary retention, we performed Holmium Laser Enucleation of the Prostate (HoLEP) and obtained tissue samples weighing 276 g and 153 g, respectively. The postoperative courses were good. CONCLUSION: We experienced two cases of sibling BPH with volumes exceeding 200 mL and successfully treated them with HoLEP. John Wiley and Sons Inc. 2022-05-09 /pmc/articles/PMC9249644/ /pubmed/35795106 http://dx.doi.org/10.1002/iju5.12467 Text en © 2022 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Ohyama, Takehiro
Endo, Fumiyasu
Shimbo, Masaki
Hattori, Kazunori
Japanese giant benign prostatic hyperplasia: Sibling cases
title Japanese giant benign prostatic hyperplasia: Sibling cases
title_full Japanese giant benign prostatic hyperplasia: Sibling cases
title_fullStr Japanese giant benign prostatic hyperplasia: Sibling cases
title_full_unstemmed Japanese giant benign prostatic hyperplasia: Sibling cases
title_short Japanese giant benign prostatic hyperplasia: Sibling cases
title_sort japanese giant benign prostatic hyperplasia: sibling cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249644/
https://www.ncbi.nlm.nih.gov/pubmed/35795106
http://dx.doi.org/10.1002/iju5.12467
work_keys_str_mv AT ohyamatakehiro japanesegiantbenignprostatichyperplasiasiblingcases
AT endofumiyasu japanesegiantbenignprostatichyperplasiasiblingcases
AT shimbomasaki japanesegiantbenignprostatichyperplasiasiblingcases
AT hattorikazunori japanesegiantbenignprostatichyperplasiasiblingcases

Ejemplares similares