In vivo generation of CAR T cells in the presence of human myeloid cells

Pre-clinical humanized mouse models are a powerful tool to evaluate immunotherapies. NSG-SGM3 mice reconstituted with human stem cells (huSGM3) develop pronounced human myeloid cells due to transgenic expression of stem cell factor, granulocyte-macrophage colony-stimulating factor, and interleukin-3...

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Detalles Bibliográficos
Autores principales: Ho, Naphang, Agarwal, Shiwani, Milani, Michela, Cantore, Alessio, Buchholz, Christian J., Thalheimer, Frederic B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249670/
https://www.ncbi.nlm.nih.gov/pubmed/35795778
http://dx.doi.org/10.1016/j.omtm.2022.06.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249670/
https://www.ncbi.nlm.nih.gov/pubmed/35795778
http://dx.doi.org/10.1016/j.omtm.2022.06.004

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