Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

Abnormal mitochondrial fragmentation by dynamin-related protein1 (Drp1) is associated with the progression of aging-associated heart diseases, including heart failure and myocardial infarction (MI). Here, we report a protective role of outer mitochondrial membrane (OMM)-localized E3 ubiquitin ligase...

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Detalles Bibliográficos
Autores principales: Tokuyama, Takeshi, Uosaki, Hideki, Sugiura, Ayumu, Nishitai, Gen, Takeda, Keisuke, Nagashima, Shun, Shiiba, Isshin, Ito, Naoki, Amo, Taku, Mohri, Satoshi, Nishimura, Akiyuki, Nishida, Motohiro, Konno, Ayumu, Hirai, Hirokazu, Ishido, Satoshi, Yoshizawa, Takahiro, Shindo, Takayuki, Takada, Shingo, Kinugawa, Shintaro, Inatome, Ryoko, Yanagi, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249672/
https://www.ncbi.nlm.nih.gov/pubmed/35789860
http://dx.doi.org/10.1016/j.isci.2022.104582

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