ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform

The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in breast carcinogenesis are completely unknown. Here, we identified high ALYREF expression as a factor for poor survival in breast cancer patients....

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Detalles Bibliográficos
Autores principales: Klec, Christiane, Knutsen, Erik, Schwarzenbacher, Daniela, Jonas, Katharina, Pasculli, Barbara, Heitzer, Ellen, Rinner, Beate, Krajina, Katarina, Prinz, Felix, Gottschalk, Benjamin, Ulz, Peter, Deutsch, Alexander, Prokesch, Andreas, Jahn, Stephan W., Lellahi, S. Mohammad, Perander, Maria, Barbano, Raffaela, Graier, Wolfgang F., Parrella, Paola, Calin, George Adrian, Pichler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249705/
https://www.ncbi.nlm.nih.gov/pubmed/35776213
http://dx.doi.org/10.1007/s00018-022-04402-2

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