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Association of mitochondrial DNA content, heteroplasmies and inter-generational transmission with autism
Mitochondria are essential for brain development. While previous studies linked dysfunctional mitochondria with autism spectrum disorder (ASD), the role of the mitochondrial genome (mtDNA) in ASD risk is largely unexplored. This study investigates the association of mtDNA heteroplasmies (co-existenc...
Autores principales: | Wang, Yiqin, Guo, Xiaoxian, Hong, Xiumei, Wang, Guoying, Pearson, Colleen, Zuckerman, Barry, Clark, Andrew G., O’Brien, Kimberly O., Wang, Xiaobin, Gu, Zhenglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249801/ https://www.ncbi.nlm.nih.gov/pubmed/35778412 http://dx.doi.org/10.1038/s41467-022-30805-7 |
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