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M2 macrophage-derived exosomal microRNA-411-5p impedes the activation of hepatic stellate cells by targeting CAMSAP1 in NASH model

Liver fibrosis is a severe stage of nonalcoholic fatty liver disease (NAFLD), which is closely associated with the activation of hepatic stellate cells (HSCs) and their interaction with macrophages. Exosomes can mediate crosstalk between macrophages and HSCs in NAFLD-associated fibrosis. We found th...

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Detalles Bibliográficos
Autores principales: Wan, Zhiping, Yang, Xiaoan, Liu, Xiaoquan, Sun, Yinfang, Yu, Piaojian, Xu, Fen, Deng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249826/
https://www.ncbi.nlm.nih.gov/pubmed/35789846
http://dx.doi.org/10.1016/j.isci.2022.104597