Systematic identification of tRNA genes in Drosophila melanogaster

Transfer RNAs (tRNAs) are ubiquitous adapter molecules that link specific codons in messenger RNA (mRNA) with their corresponding amino acids during protein synthesis. The tRNA genes of Drosophila have been investigated for over half a century but have lacked systematic identification and nomenclatu...

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Detalles Bibliográficos
Autores principales: Marygold, Steven J, Chan, Patricia P, Lowe, Todd M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Data Updates
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249942/
https://www.ncbi.nlm.nih.gov/pubmed/35789696
http://dx.doi.org/10.17912/micropub.biology.000560
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author Marygold, Steven J
Chan, Patricia P
Lowe, Todd M
author_facet Marygold, Steven J
Chan, Patricia P
Lowe, Todd M
author_sort Marygold, Steven J
collection PubMed
description Transfer RNAs (tRNAs) are ubiquitous adapter molecules that link specific codons in messenger RNA (mRNA) with their corresponding amino acids during protein synthesis. The tRNA genes of Drosophila have been investigated for over half a century but have lacked systematic identification and nomenclature. Here, we review and integrate data within FlyBase and the Genomic tRNA Database (GtRNAdb) to identify the full complement of tRNA genes in the D. melanogaster nuclear and mitochondrial genomes. We apply a logical and informative nomenclature to all tRNA genes, and provide an overview of their characteristics and genomic features.
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spelling pubmed-92499422022-07-03 Systematic identification of tRNA genes in Drosophila melanogaster Marygold, Steven J Chan, Patricia P Lowe, Todd M MicroPubl Biol Data Updates Transfer RNAs (tRNAs) are ubiquitous adapter molecules that link specific codons in messenger RNA (mRNA) with their corresponding amino acids during protein synthesis. The tRNA genes of Drosophila have been investigated for over half a century but have lacked systematic identification and nomenclature. Here, we review and integrate data within FlyBase and the Genomic tRNA Database (GtRNAdb) to identify the full complement of tRNA genes in the D. melanogaster nuclear and mitochondrial genomes. We apply a logical and informative nomenclature to all tRNA genes, and provide an overview of their characteristics and genomic features. Caltech Library 2022-05-01 /pmc/articles/PMC9249942/ /pubmed/35789696 http://dx.doi.org/10.17912/micropub.biology.000560 Text en Copyright: © 2022 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Data Updates
Marygold, Steven J
Chan, Patricia P
Lowe, Todd M
Systematic identification of tRNA genes in Drosophila melanogaster
title Systematic identification of tRNA genes in Drosophila melanogaster
title_full Systematic identification of tRNA genes in Drosophila melanogaster
title_fullStr Systematic identification of tRNA genes in Drosophila melanogaster
title_full_unstemmed Systematic identification of tRNA genes in Drosophila melanogaster
title_short Systematic identification of tRNA genes in Drosophila melanogaster
title_sort systematic identification of trna genes in drosophila melanogaster
topic Data Updates
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249942/
https://www.ncbi.nlm.nih.gov/pubmed/35789696
http://dx.doi.org/10.17912/micropub.biology.000560
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