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NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability

TRK fusions are rare but targetable mutations which occur across a wide variety of cancer types. We report the prevalence of approximately 0.7% for NTRK‐positive colorectal cancer (CRC) by genetically profiling 2519 colonic and rectal tumors. The aberrations of APC and TP53 frequently co‐occurred wi...

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Detalles Bibliográficos
Autores principales:	Wang, Hui, Li, Zhi‐Wei, Ou, Qiuxiang, Wu, Xue, Nagasaka, Misako, Shao, Yang, Ou, Sai‐Hong Ignatius, Yang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249987/ https://www.ncbi.nlm.nih.gov/pubmed/35506567 http://dx.doi.org/10.1002/cam4.4561

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