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Serum exosomal miR‐16‐5p functions as a tumor inhibitor and a new biomarker for PD‐L1 inhibitor‐dependent immunotherapy in lung adenocarcinoma by regulating PD‐L1 expression
OBJECTIVES: We aimed at investigating whether serum exosomal miR‐16‐5p could be utilized as an immunotherapy biomarker in lung adenocarcinoma (LUAD) patients administered by programmed cell death ligand‐1 (PD‐L1) inhibitors, and to evaluate its functions in LUAD progression. METHODS: Sixty LUAD suff...
Autores principales: | Chen, Hua‐Lin, Luo, Yi‐Ping, Lin, Mu‐Wen, Peng, Xiao‐Xia, Liu, Mei‐Liang, Wang, Yong‐Cun, Li, Shu‐Jun, Yang, Dong‐Hong, Yang, Zhi‐Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249988/ https://www.ncbi.nlm.nih.gov/pubmed/35347894 http://dx.doi.org/10.1002/cam4.4638 |
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