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Single-cell transcriptional regulation and genetic evolution of neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer, with a 10% five-year survival rate. However, little is known about its origin and the mechanisms governing its emergence. Our study characterized ADPC and NEPC in prostate tumors from 7 patients using scRNA-seq. First, we...

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Detalles Bibliográficos
Autores principales:	Wang, Ziwei, Wang, Tao, Hong, Danni, Dong, Baijun, Wang, Yan, Huang, Huaqiang, Zhang, Wenhui, Lian, Bijun, Ji, Boyao, Shi, Haoqing, Qu, Min, Gao, Xu, Li, Daofeng, Collins, Colin, Wei, Gonghong, Xu, Chuanliang, Lee, Hyung Joo, Huang, Jialiang, Li, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250006/ https://www.ncbi.nlm.nih.gov/pubmed/35789834 http://dx.doi.org/10.1016/j.isci.2022.104576

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